{"id":6959,"date":"2024-03-18T14:16:53","date_gmt":"2024-03-18T13:16:53","guid":{"rendered":"https:\/\/www.proanima.fr\/science-dialogue-serie-de-panels-de-discussion\/"},"modified":"2024-10-21T10:37:09","modified_gmt":"2024-10-21T09:37:09","slug":"science-dialogue-serie-de-panels-de-discussion","status":"publish","type":"page","link":"https:\/\/www.proanima.fr\/en\/science-dialogue-serie-de-panels-de-discussion\/","title":{"rendered":"Science &amp; Dialogue: Panel Discussion Series"},"content":{"rendered":"<h2><span class=\"ez-toc-section\" id=\"presentation\"><\/span>Presentation<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>In order to contribute to greater acceptance of NAMs (reliability, robustness and method validation), the Pro Anima Scientific Committee, supported by <a href=\"https:\/\/www.eu-parc.eu\/\" target=\"_blank\" rel=\"noopener\">PARC<\/a> and the <a href=\"https:\/\/www.fc3r.com\/\" target=\"_blank\" rel=\"noopener\">FC3R<\/a>, is organizing and leading a series of discussions with key players (researchers, industry, regulators).<\/p>\n<p>In light of the challenges notably<a href=\"https:\/\/single-market-economy.ec.europa.eu\/system\/files\/2023-12\/4.5.%2020231212_PARC_T22_NGRAroute_Herzle_v.2.pdf\" target=\"_blank\" rel=\"noopener\"> identified by PARC<\/a> as part of its roadmap for NGRA (Next Generation Risk Assessment), the discussions revolve around the following themes: toxicology, NAMs and regulation.<\/p>\n<p>Panel discussions are <strong>online<\/strong>, <strong>free of charge<\/strong>, <strong>and registration is required<\/strong>.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"objectives\"><\/span>Objectives<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<ul>\n<li>Contribute to a greater acceptance of New Approach Methodologies and Non-Animal Methods (NAMs) for toxicology testing and regulation<\/li>\n<li>Foster cross-disciplinary dialogue between research, industry and regulatory operators<\/li>\n<li>Identify current and future scientific and regulatory obstacles and solutions<\/li>\n<li>Create content to raise awareness and educate the general public about these advances<\/li>\n<\/ul>\n<h2><\/h2>\n<h2><span class=\"ez-toc-section\" id=\"panel_discussion_coming_up\"><\/span>Panel Discussion Coming Up<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<h4>Next panel discussion in&nbsp;2025<\/h4>\n<p>&nbsp;<\/p>\n<h2><span class=\"ez-toc-section\" id=\"previous_panel_discussions\"><\/span>Previous Panel Discussions<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<h3 style=\"text-align: center;\"><span class=\"OYPEnA text-decoration-underline text-strikethrough-none\">Session 3 : <span class=\"OYPEnA font-feature-liga-off font-feature-clig-off font-feature-calt-off text-decoration-none text-strikethrough-none\">Recherche non animale\u2009\u2014\u2009<\/span><\/span><span class=\"OYPEnA text-decoration-underline text-strikethrough-none\"><span class=\"OYPEnA font-feature-liga-off font-feature-clig-off font-feature-calt-off text-decoration-none text-strikethrough-none\">Quelles approches pour sensibiliser les publics ?<\/span> (In french)<\/span><\/h3>\n<p style=\"text-align: center;\">\n<\/p><p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-8457\" src=\"https:\/\/www.proanima.fr\/wp-content\/uploads\/2024\/10\/202410-News-CSPA-1200x700-1.png\" alt width=\"1200\" height=\"700\" srcset=\"https:\/\/www.proanima.fr\/wp-content\/uploads\/2024\/10\/202410-News-CSPA-1200x700-1.png 1200w, https:\/\/www.proanima.fr\/wp-content\/uploads\/2024\/10\/202410-News-CSPA-1200x700-1-300x175.png 300w, https:\/\/www.proanima.fr\/wp-content\/uploads\/2024\/10\/202410-News-CSPA-1200x700-1-1024x597.png 1024w, https:\/\/www.proanima.fr\/wp-content\/uploads\/2024\/10\/202410-News-CSPA-1200x700-1-768x448.png 768w, https:\/\/www.proanima.fr\/wp-content\/uploads\/2024\/10\/202410-News-CSPA-1200x700-1-624x364.png 624w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\"><\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: center;\">\n<\/p><p>The Pro Anima Scientific Committee was honored to co-organize the 3rd edition in partnership with the Foundation for Medical Research (FRM). After discussing the central issues of regulatory acceptance and harmonization of NAMs in the first two panels, with internationally renowned speakers, this third panel will focus on the essential question of public awareness, the methods, and challenges that researchers, institutions, and the media are tackling to meet the needs for trust and information in civil society in the face of new 21st-century science, which is more reliable and respectful of human, animal, and environmental health (according to the One Health or global health concept).<\/p>\n<p>The session was co-moderated by <strong>Dr Athanassia Sotiropoulos<\/strong>, Director of the French 3R Centre (FC3R) and <strong>Dr Lilas Courtot<\/strong>, Scientific Director of the Pro Anima Scientific Committee. The two moderators had the pleasure of discussing and giving the floor to leading speakers on the issues of new research methods, health and public information, namely <strong>Dr Val\u00e9rie Lemarchandel<\/strong>, Scientific Director of the FRM and <strong>Dr St\u00e9phanie Descroix<\/strong>, Research Director at the Institut Curie.<\/p>\n<p><strong>Many thanks<\/strong> to our panelists and moderators for these rich, complex and stimulating exchanges. And thanks also to the participants and to the Fondation pour la Recherche M\u00e9dicale for its participation and support in organizing this event. <strong>We will soon be publishing a report to share these reflections with as many people as possible, and continue to make progress on these vital issues<\/strong>.<\/p>\n<p>\u2014<\/p>\n<h3><span class=\"ez-toc-section\" id=\"panelists\"><\/span><strong>Panelists<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-8278 alignleft\" src=\"https:\/\/www.proanima.fr\/wp-content\/uploads\/2024\/09\/20240904-vignette-hello-asso-2.png\" alt width=\"231\" height=\"198\" srcset=\"https:\/\/www.proanima.fr\/wp-content\/uploads\/2024\/09\/20240904-vignette-hello-asso-2.png 628w, https:\/\/www.proanima.fr\/wp-content\/uploads\/2024\/09\/20240904-vignette-hello-asso-2-300x258.png 300w, https:\/\/www.proanima.fr\/wp-content\/uploads\/2024\/09\/20240904-vignette-hello-asso-2-624x537.png 624w\" sizes=\"auto, (max-width: 231px) 100vw, 231px\"><\/p>\n<p><strong>Dr Val\u00e9rie Lemarchandel<\/strong><\/p>\n<p>Val\u00e9rie Lemarchandel holds a doctorate in biology and is a research director at the CNRS. Between 1989 and 2006, she carried out research in haematology, embryonic development and molecular genetics. She was then in charge of scientific communication for 4 years within the management of the CNRS Institute of Biological Sciences.<\/p>\n<p>Since 2010, she has been Scientific Director of the Fondation pour la Recherche M\u00e9dicale and a member of its Executive Board.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-8276 alignleft\" src=\"https:\/\/www.proanima.fr\/wp-content\/uploads\/2024\/09\/20240904-vignette-hello-asso-3.png\" alt width=\"230\" height=\"198\" srcset=\"https:\/\/www.proanima.fr\/wp-content\/uploads\/2024\/09\/20240904-vignette-hello-asso-3.png 628w, https:\/\/www.proanima.fr\/wp-content\/uploads\/2024\/09\/20240904-vignette-hello-asso-3-300x258.png 300w, https:\/\/www.proanima.fr\/wp-content\/uploads\/2024\/09\/20240904-vignette-hello-asso-3-624x537.png 624w\" sizes=\"auto, (max-width: 230px) 100vw, 230px\"><\/p>\n<p><strong>Dr St\u00e9phanie Descroix<\/strong><\/p>\n<p>St\u00e9phanie Descroix is currently Director of Research at the CNRS and head of the Macromolecules and Microsystems in Biology and Medicine research team at the Institut Curie Paris and the Institut Pierre Gilles De Gennes. Her team is internationally recognised for the development of microfluidic devices and concepts (organs-on-a-chip) for fundamental biology, biophysics and the clinic, with a strong commitment to technology transfer in the field of medicine and life sciences. She is deputy director of the French national network on microfluidics (GDR MNF). She is the author of over 90 scientific publications and has participated in several highly selective European projects. In 2016, she successfully co-launched the microfluidics-based company Inorevia, which has received awards from several prestigious French and European institutions. More recently, St\u00e9phanie has distinguished herself for her contribution to the MED-OOC project (Organs and Organoids-on-Chips), supported by CNRS, Inserm and CEA, which aims to develop a new generation of organs and organoids on chips, capable of mimicking the physiology or pathology of the patient\u2019s organ, with the aim of using it for personalised medicine.<\/p>\n<h2><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-8294 alignleft\" src=\"https:\/\/www.proanima.fr\/wp-content\/uploads\/2024\/09\/20240904-vignette-hello-asso-8.png\" alt width=\"231\" height=\"199\" srcset=\"https:\/\/www.proanima.fr\/wp-content\/uploads\/2024\/09\/20240904-vignette-hello-asso-8.png 628w, https:\/\/www.proanima.fr\/wp-content\/uploads\/2024\/09\/20240904-vignette-hello-asso-8-300x258.png 300w, https:\/\/www.proanima.fr\/wp-content\/uploads\/2024\/09\/20240904-vignette-hello-asso-8-624x537.png 624w\" sizes=\"auto, (max-width: 231px) 100vw, 231px\"><\/h2>\n<p><strong>Dr Luigi Formicola<\/strong><\/p>\n<p>Luigi Formicola is co-founder and COO of <a href=\"https:\/\/exadex-innov.com\/\" target=\"_blank\" rel=\"noopener\">ExAdEx-Innov<\/a>, an innovative startup with the ambition to revolutionize adipose tissue research with patented ex vivo models that faithfully reproduce human&nbsp;fat.<\/p>\n<p>With a PhD in cell biology, he has over ten years\u2019 experience in research project management and technology transfer in the biotech sector, as well as in drug development. He has thus witnessed developments in preclinical research and the emergence of alternative solutions aimed at reducing the need for animal experimentation while improving the predictability of clinical trials.our paths will&nbsp;cross<\/p>\n<p>&nbsp;<\/p>\n<hr>\n<h2><\/h2>\n<h3><span class=\"OYPEnA text-decoration-underline text-strikethrough-none\">Session 2: Harmonization of NAMs\u2009\u2014\u2009Can it really be global? (in English)<\/span><\/h3>\n<p style=\"text-align: center;\"><span style=\"text-decoration: underline;\"><strong>Thursday June 27, 1\u2009\u2013\u20092:15pm (CET)<\/strong><\/span><\/p>\n<p>For our first session on defining criteria for the regulatory acceptance of NAMs, we had the honor and pleasure to welcome Dr Carl Westmoreland (Unilever), Pr Ellen Fritsche (DNTOX &amp; SCAHT) and Dr Clive Roper for what has been a fascinating and fruitful discussion.<\/p>\n<p>For this session 2, we wanted to explore and discuss current challenges, opportunities, and ongoing actions in favor of harmonizing NAMs, to ensure it can and will be regulated \/ accepted worldwide, and under the same criteria. We had the privilege to welcome <strong>Dr Nicole Kleinstreuer<\/strong>, NICEATM Director at National Institute of Environmental Health Sciences (NIEHS), <strong>Dr Nina Hobi<\/strong>, CEO at AlveoliX and <strong>Dr Surat Parvatam<\/strong>, Senior Strategist at HSI&nbsp;India.<\/p>\n<p>We also were delighted to moderate the session with <strong>Prof Merel Ritskes-Hoitinga<\/strong>, from the University of Utrecht.<\/p>\n<h3 style=\"text-align: center;\"><span class=\"ez-toc-section\" id=\"watch_the_replay\"><\/span>Watch the replay<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><iframe loading=\"lazy\" title=\"Science &amp; Dialogue - Session 2: Harmonization of NAMs, can it really be global?\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/7E-w-85aAcQ?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe><\/p>\n<p>&nbsp;<\/p>\n<hr>\n<p>&nbsp;<\/p>\n<h3><span class=\"OYPEnA text-decoration-underline text-strikethrough-none\">Session 1: <\/span><span class=\"OYPEnA text-strikethrough-none text-decoration-none\">Regulatory acceptance of NAMs\u2009\u2014\u2009How to define criteria?<\/span><\/h3>\n<p style=\"text-align: center;\"><strong>Thursday April 25, 1\u2009\u2013\u20092pm&nbsp;CET<\/strong><\/p>\n<p>It is getting clearer now that if we want to accelerate the adoption of NAMs (non-animal new approach methodologies), there is a need for more global harmonization of the criteria used for qualification of the techniques and validation of those criteria. To ensure confidence in new models, regulatory agencies need these to be qualified, confirming they are robust, that they faithfully mimic human level functionalities and that it is appropriate for specific contexts of use (COU).&nbsp;<strong>This panel discussion tackled this challenging objective of defining acceptance criteria<\/strong>.<\/p>\n<p>On this occasion, we had the pleasure to welcome:<\/p>\n<h3 style=\"text-align: center;\"><span class=\"ez-toc-section\" id=\"watch_the_replay-2\"><\/span>Watch the replay<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><iframe loading=\"lazy\" title=\"Science &amp; Dialogue - Session 1: Regulatory Acceptance of NAMs, how to define criteria?\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/3ra6imApryU?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe><\/p>\n<p>&nbsp;<\/p>\n<hr>\n<p>&nbsp;<\/p>\n<h2><span class=\"ez-toc-section\" id=\"supported_by\"><\/span>Supported by<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<div id=\"gallery-1\" class=\"gallery galleryid-6959 gallery-columns-3 gallery-size-thumbnail\"><figure class=\"gallery-item\">\n\t\t\t<div class=\"gallery-icon landscape\">\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"150\" height=\"150\" src=\"https:\/\/www.proanima.fr\/wp-content\/uploads\/2024\/03\/S-DOTS-BLUE-150x150.png\" class=\"attachment-thumbnail size-thumbnail\" alt>\n\t\t\t<\/div><\/figure><figure class=\"gallery-item\">\n\t\t\t<div class=\"gallery-icon landscape\">\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"150\" height=\"150\" src=\"https:\/\/www.proanima.fr\/wp-content\/uploads\/2024\/03\/FC3RLogo_old-150x150.png\" class=\"attachment-thumbnail size-thumbnail\" alt srcset=\"https:\/\/www.proanima.fr\/wp-content\/uploads\/2024\/03\/FC3RLogo_old-150x150.png 150w, https:\/\/www.proanima.fr\/wp-content\/uploads\/2024\/03\/FC3RLogo_old-300x300.png 300w, https:\/\/www.proanima.fr\/wp-content\/uploads\/2024\/03\/FC3RLogo_old-1024x1024.png 1024w, https:\/\/www.proanima.fr\/wp-content\/uploads\/2024\/03\/FC3RLogo_old-768x768.png 768w, https:\/\/www.proanima.fr\/wp-content\/uploads\/2024\/03\/FC3RLogo_old-1536x1536.png 1536w, https:\/\/www.proanima.fr\/wp-content\/uploads\/2024\/03\/FC3RLogo_old-624x624.png 624w, https:\/\/www.proanima.fr\/wp-content\/uploads\/2024\/03\/FC3RLogo_old.png 1772w\" sizes=\"auto, (max-width: 150px) 100vw, 150px\">\n\t\t\t<\/div><\/figure><figure class=\"gallery-item\">\n\t\t\t<div class=\"gallery-icon portrait\">\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"150\" height=\"150\" src=\"https:\/\/www.proanima.fr\/wp-content\/uploads\/2024\/03\/Logo_ATC-150x150.png\" class=\"attachment-thumbnail size-thumbnail\" alt srcset=\"https:\/\/www.proanima.fr\/wp-content\/uploads\/2024\/03\/Logo_ATC-150x150.png 150w, https:\/\/www.proanima.fr\/wp-content\/uploads\/2024\/03\/Logo_ATC-300x300.png 300w, https:\/\/www.proanima.fr\/wp-content\/uploads\/2024\/03\/Logo_ATC-768x769.png 768w, https:\/\/www.proanima.fr\/wp-content\/uploads\/2024\/03\/Logo_ATC-624x625.png 624w, https:\/\/www.proanima.fr\/wp-content\/uploads\/2024\/03\/Logo_ATC.png 944w\" sizes=\"auto, (max-width: 150px) 100vw, 150px\">\n\t\t\t<\/div><\/figure>\n\t\t<\/div>\n\n<p><strong>&nbsp;<\/strong><\/p>\n<div id=\"simple-translate\" class=\"simple-translate-system-theme\">\n<div>\n<div class=\"simple-translate-button isShow\" style=\"background-image: url('moz-extension:\/\/73aefce4-c90e-4898-b3b5-b46df75fd59a\/icons\/512.png'); height: 22px; width: 22px; top: 679px; left: 109px;\"><\/div>\n<div class=\"simple-translate-panel \" style=\"width: 300px; height: 200px; top: 0px; left: 0px; font-size: 13px;\">\n<div class=\"simple-translate-result-wrapper\" style=\"overflow: hidden;\">\n<div class=\"simple-translate-move\" draggable=\"true\"><\/div>\n<div class=\"simple-translate-result-contents\">\n<p class=\"simple-translate-candidate\" dir=\"auto\">\n<\/p><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Presentation In order to contribute to greater acceptance of NAMs (reliability, robustness and method validation), the Pro Anima Scientific Committee, supported by PARC and the FC3R, is organizing and leading a series of discussions with key players (researchers, industry, regulators).&nbsp;[\u2026]<\/p>\n","protected":false},"author":1,"featured_media":6947,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"wp_typography_post_enhancements_disabled":false,"footnotes":""},"class_list":["post-6959","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - 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