{"id":4112,"date":"2023-02-13T08:42:49","date_gmt":"2023-02-13T07:42:49","guid":{"rendered":"https:\/\/www.proanima.fr\/ethicscience\/prix-ethicscience\/utilisation-de-la-tumeur-du-patient\/"},"modified":"2023-07-28T09:21:15","modified_gmt":"2023-07-28T08:21:15","slug":"use-of-the-patients-tumor","status":"publish","type":"page","link":"https:\/\/www.proanima.fr\/en\/prix-ethicscience\/use-of-the-patients-tumor\/","title":{"rendered":"Use of the patient\u2019s tumor"},"content":{"rendered":"<h2><span class=\"ez-toc-section\" id=\"category_development_and_applicability\"><\/span>Category: Development and Applicability<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>(Practical research)<\/p>\n<div class=\"encadre_centre\" style=\"text-align: center;\"><strong>Dr Julien Marie and Sophie L\u00e9on<br>\nINSERM, CNRS<br>\n<\/strong><br>\n<strong>CRCL\u2009\u2014L\u00e9on B\u00e9rard Hospital Center \u2013&nbsp;Lyon<\/strong><\/div>\n<p>The last 20 years have seen an upsurge in the use of animals in research, particularly against cancer, due to the lack of an alternative approach that maintains the pathophysiological aspect. Sophie LEON and Julien MARIE have developed a method that does not use any animals and that meets the expectations of a maximum of researchers.<\/p>\n<p><strong>This innovative, rapid, easy-to-implement ex-vivo approach involves living maintenance of the patient\u2019s tumor obtained after surgery or biopsy.<\/strong><\/p>\n<p><strong>Highly reproducible, preserving the biological integrity and the cellular interactions within the tissue, including the immune system, this method makes it possible to address a large number of experimental questions in academic research and corresponds to the waiting criteria of industrial laboratories.<\/strong><\/p>\n<p><strong>The objective of Sophie LEON and Julien MARIE is to offer this method to as many researchers as possible.<\/strong><\/p>\n<p><strong>Validated and published on three types of cancer (breast, lung, melanoma), this technology will be adapted to other cancers, in particular those with a poor prognosis (pancreas), and to pediatric forms to accelerate the availability of new therapeutic actors.<\/strong> This approach can also be applied to healthy tissues and therefore be offered to all biology researchers in the academic and industrial world.<\/p>\n<p>The duration of the project funded by the Descroix-Vernier EthicScience Prize is estimated at 2&nbsp;years.<\/p>\n<p>&nbsp;<\/p>\n<div id=\"attachment_5756\" style=\"width: 1034px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-5756\" class=\"size-large wp-image-5756\" src=\"https:\/\/www.proanima.fr\/wp-content\/uploads\/2023\/07\/PHOTO-JULIEN-MARIE-SOPHIE-LEON-CRCL-LYON-Image-06-12-2022-a-16.39-1024x662.jpg\" alt width=\"1024\" height=\"662\" srcset=\"https:\/\/www.proanima.fr\/wp-content\/uploads\/2023\/07\/PHOTO-JULIEN-MARIE-SOPHIE-LEON-CRCL-LYON-Image-06-12-2022-a-16.39-1024x662.jpg 1024w, https:\/\/www.proanima.fr\/wp-content\/uploads\/2023\/07\/PHOTO-JULIEN-MARIE-SOPHIE-LEON-CRCL-LYON-Image-06-12-2022-a-16.39-300x194.jpg 300w, https:\/\/www.proanima.fr\/wp-content\/uploads\/2023\/07\/PHOTO-JULIEN-MARIE-SOPHIE-LEON-CRCL-LYON-Image-06-12-2022-a-16.39-768x496.jpg 768w, https:\/\/www.proanima.fr\/wp-content\/uploads\/2023\/07\/PHOTO-JULIEN-MARIE-SOPHIE-LEON-CRCL-LYON-Image-06-12-2022-a-16.39-1536x993.jpg 1536w, https:\/\/www.proanima.fr\/wp-content\/uploads\/2023\/07\/PHOTO-JULIEN-MARIE-SOPHIE-LEON-CRCL-LYON-Image-06-12-2022-a-16.39-2048x1323.jpg 2048w, https:\/\/www.proanima.fr\/wp-content\/uploads\/2023\/07\/PHOTO-JULIEN-MARIE-SOPHIE-LEON-CRCL-LYON-Image-06-12-2022-a-16.39-624x403.jpg 624w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\"><p id=\"caption-attachment-5756\" class=\"wp-caption-text\">Cr\u00e9dit image&nbsp;: Dr Julien Marie et Sophie L\u00e9on, Centre de Recherche en Canc\u00e9rologie de&nbsp;Lyon<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Category: Development and Applicability (Practical research) Dr Julien Marie and Sophie L\u00e9on INSERM, CNRS CRCL\u2009\u2014L\u00e9on B\u00e9rard Hospital Center \u2013&nbsp;Lyon The last 20 years have seen an upsurge in the use of animals in research, particularly against cancer, due to&nbsp;the&nbsp;[\u2026]<\/p>\n","protected":false},"author":1,"featured_media":4063,"parent":3220,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"wp_typography_post_enhancements_disabled":false,"footnotes":""},"class_list":["post-4112","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - 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