{"id":4108,"date":"2023-02-13T08:34:51","date_gmt":"2023-02-13T07:34:51","guid":{"rendered":"https:\/\/www.proanima.fr\/ethicscience\/3d-glimpse-une-tumeur-sur-puce-pour-combattre-le-glioblastome\/"},"modified":"2023-03-01T17:25:20","modified_gmt":"2023-03-01T16:25:20","slug":"3d-glimpse-a-tumor-on-a-chip-to-fight-glioblastoma","status":"publish","type":"page","link":"https:\/\/www.proanima.fr\/en\/ethicscience\/3d-glimpse-a-tumor-on-a-chip-to-fight-glioblastoma\/","title":{"rendered":"3D Glimpse"},"content":{"rendered":"<h2><span class=\"ez-toc-section\" id=\"category_innovation\"><\/span>Category: INNOVATION<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>(New concepts and technology transfer)<\/p>\n<div class=\"encadre_centre\">\n<p style=\"text-align: center;\"><strong>Dr Agathe Figarol<\/strong><\/p>\n<p style=\"text-align: center;\"><strong>Franche-Comt\u00e9 University, ISIFC, FEMTO-ST Institute<\/strong><\/p>\n<\/div>\n<p>Glioblastoma multiforme is the most common and aggressive brain tumour, with a survival after diagnosis of approximately 12 months. Preclinical research to combat it is caught between overly simplistic models and animal studies with ethical issues and uncertainties related to inter-species differences.<\/p>\n<p>This project will develop a model closer to humans: a tumor-on-microchip in the laboratory.<\/p>\n<p>In a gel representing the tumor microenvironment, different types of human cells will organize themselves in 3D to form micro-vessels. These will be infused to mimic blood flow, and study the transport and effectiveness of new nano-drugs.<\/p>\n<p><strong>A prototype of this tumor on a chip is emerging, and a finalized version should be available within a year and a half. The goal is to better understand and treat brain cancer, by proposing an innovative alternative model to animal experimentation.<\/strong><\/p>\n<div id=\"attachment_4034\" style=\"width: 1034px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-4034\" class=\"size-full wp-image-4034\" src=\"https:\/\/www.proanima.fr\/wp-content\/uploads\/2023\/02\/PHOTO-FIGAROL-FEMTO-BESANCON-2022-12-08-Bind-Team.jpeg\" alt width=\"1024\" height=\"768\" srcset=\"https:\/\/www.proanima.fr\/wp-content\/uploads\/2023\/02\/PHOTO-FIGAROL-FEMTO-BESANCON-2022-12-08-Bind-Team.jpeg 1024w, https:\/\/www.proanima.fr\/wp-content\/uploads\/2023\/02\/PHOTO-FIGAROL-FEMTO-BESANCON-2022-12-08-Bind-Team-300x225.jpeg 300w, https:\/\/www.proanima.fr\/wp-content\/uploads\/2023\/02\/PHOTO-FIGAROL-FEMTO-BESANCON-2022-12-08-Bind-Team-768x576.jpeg 768w, https:\/\/www.proanima.fr\/wp-content\/uploads\/2023\/02\/PHOTO-FIGAROL-FEMTO-BESANCON-2022-12-08-Bind-Team-320x240.jpeg 320w, https:\/\/www.proanima.fr\/wp-content\/uploads\/2023\/02\/PHOTO-FIGAROL-FEMTO-BESANCON-2022-12-08-Bind-Team-624x468.jpeg 624w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\"><p id=\"caption-attachment-4034\" class=\"wp-caption-text\">Cr\u00e9dit image&nbsp;: Agathe Figarol, \u00e9quipe BioMicroDevices, Institut FEMTO ST, Universit\u00e9 Franche Comt\u00e9<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Category: INNOVATION (New concepts and technology transfer) Dr Agathe Figarol Franche-Comt\u00e9 University, ISIFC, FEMTO-ST Institute Glioblastoma multiforme is the most common and aggressive brain tumour, with a survival after diagnosis of approximately 12 months. Preclinical research to combat it&nbsp;is&nbsp;[\u2026]<\/p>\n","protected":false},"author":1,"featured_media":4061,"parent":1246,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"wp_typography_post_enhancements_disabled":false,"footnotes":""},"class_list":["post-4108","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>3D Glimpse - Pro Anima<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.proanima.fr\/en\/ethicscience\/3d-glimpse-a-tumor-on-a-chip-to-fight-glioblastoma\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"3D Glimpse - Pro Anima\" \/>\n<meta property=\"og:description\" content=\"Category: INNOVATION (New concepts and technology transfer) Dr Agathe Figarol Franche-Comt\u00e9 University, ISIFC, FEMTO-ST Institute Glioblastoma multiforme is the most common and aggressive brain tumour, with a survival after diagnosis of approximately 12 months. 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